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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PEX1
All Species:
16.36
Human Site:
S1172
Identified Species:
22.5
UniProt:
O43933
Number Species:
16
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43933
NP_000457.1
1283
142867
S1172
P
G
K
D
Q
L
F
S
Q
P
P
V
L
R
T
Chimpanzee
Pan troglodytes
XP_519198
1283
142803
S1172
P
G
K
E
Q
L
F
S
Q
P
P
V
L
R
T
Rhesus Macaque
Macaca mulatta
XP_001101055
1278
142022
S1167
P
G
K
D
Q
L
F
S
Q
P
P
V
L
R
T
Dog
Lupus familis
XP_532459
1267
140567
S1156
A
G
K
E
Q
S
S
S
R
P
P
V
L
R
T
Cat
Felis silvestris
Mouse
Mus musculus
Q5BL07
1284
141409
T1173
P
G
K
D
P
L
F
T
Q
H
P
V
F
R
T
Rat
Rattus norvegicus
P46462
806
89330
K696
E
I
C
Q
R
A
C
K
L
A
I
R
E
S
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520628
1178
126535
H1066
S
G
P
S
S
G
L
H
D
L
A
G
L
L
G
Chicken
Gallus gallus
XP_418655
1290
143066
Q1180
Q
R
D
T
A
L
S
Q
P
S
M
L
R
T
V
Frog
Xenopus laevis
P23787
805
89193
C695
T
E
I
C
Q
R
A
C
K
L
A
I
R
E
S
Zebra Danio
Brachydanio rerio
Q7ZU99
806
89405
K696
E
I
C
Q
R
A
C
K
L
A
I
R
E
S
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7KN62
801
88841
A691
L
T
E
I
C
Q
R
A
C
K
L
A
I
R
Q
Honey Bee
Apis mellifera
XP_397107
1069
120490
L959
A
V
V
T
Q
A
R
L
S
A
L
E
N
A
I
Nematode Worm
Caenorhab. elegans
P54812
810
89622
C700
T
E
I
C
Q
R
A
C
K
L
A
I
R
E
S
Sea Urchin
Strong. purpuratus
XP_797089
1508
166130
V1397
P
P
P
Q
Q
R
V
V
Y
M
P
T
L
R
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SCN8
815
90322
E705
S
C
K
Y
A
I
R
E
N
I
E
K
D
I
E
Baker's Yeast
Sacchar. cerevisiae
P24004
1043
117258
D933
H
R
W
L
S
A
A
D
Q
S
E
V
V
P
G
Red Bread Mold
Neurospora crassa
Q7SGP2
1381
148356
V1261
K
E
D
I
S
V
M
V
T
E
Q
D
F
L
D
Conservation
Percent
Protein Identity:
100
99.6
92.8
86.4
N.A.
82
23.3
N.A.
52.4
62.4
22.9
22.8
N.A.
23.6
27.6
22.1
35.2
Protein Similarity:
100
100
94.9
92
N.A.
89.5
39.2
N.A.
66
77.6
38.6
39
N.A.
37.6
46.7
38.4
53.2
P-Site Identity:
100
93.3
100
66.6
N.A.
73.3
0
N.A.
13.3
6.6
6.6
0
N.A.
6.6
6.6
6.6
33.3
P-Site Similarity:
100
100
100
80
N.A.
80
6.6
N.A.
13.3
13.3
26.6
6.6
N.A.
26.6
6.6
26.6
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
23.5
25.7
21.4
Protein Similarity:
N.A.
N.A.
N.A.
38.5
45.2
40.9
P-Site Identity:
N.A.
N.A.
N.A.
6.6
13.3
0
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
20
6.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
0
0
0
12
24
18
6
0
18
18
6
0
6
0
% A
% Cys:
0
6
12
12
6
0
12
12
6
0
0
0
0
0
0
% C
% Asp:
0
0
12
18
0
0
0
6
6
0
0
6
6
0
12
% D
% Glu:
12
18
6
12
0
0
0
6
0
6
12
6
12
12
6
% E
% Phe:
0
0
0
0
0
0
24
0
0
0
0
0
12
0
0
% F
% Gly:
0
36
0
0
0
6
0
0
0
0
0
6
0
0
12
% G
% His:
6
0
0
0
0
0
0
6
0
6
0
0
0
0
0
% H
% Ile:
0
12
12
12
0
6
0
0
0
6
12
12
6
6
18
% I
% Lys:
6
0
36
0
0
0
0
12
12
6
0
6
0
0
0
% K
% Leu:
6
0
0
6
0
30
6
6
12
18
12
6
36
12
0
% L
% Met:
0
0
0
0
0
0
6
0
0
6
6
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
6
0
0
0
6
0
0
% N
% Pro:
30
6
12
0
6
0
0
0
6
24
36
0
0
6
0
% P
% Gln:
6
0
0
18
48
6
0
6
30
0
6
0
0
0
6
% Q
% Arg:
0
12
0
0
12
18
18
0
6
0
0
12
18
42
0
% R
% Ser:
12
0
0
6
18
6
12
24
6
12
0
0
0
12
12
% S
% Thr:
12
6
0
12
0
0
0
6
6
0
0
6
0
6
30
% T
% Val:
0
6
6
0
0
6
6
12
0
0
0
36
6
0
6
% V
% Trp:
0
0
6
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
6
0
0
0
0
6
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _